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ADMET

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Date: 29-Jun-15 to 30-Jun-15
Location: Marriott Hotel Regents Park / London / United Kingdom
Category: Healthcare & Pharmaceuticals Conferences & Trade Fairs

SMi’s10th Annual ADMET conference will provide essential insight into the latest novel technologies being used in the field of Predictive Toxicology and ADME/Tox. With drug induced liver and Cardiotoxicity still being major causes of drug attrition rates, the programme will feature case studies on development of human cellular models and state-of-the-art in vitro used to assess toxicity. This is a must attend event if you want to be at the forefront of pharmacokinetic/pharmacodynamic models; drug transporter assays in drug discovery; time-dependent inhibition screens in early drug discovery; the system-dependent inhibition of CYP enzymes and the integrating predictive toxicology framework.

Reasons why you should attend:

•In vitro models and technologies for detecting Cardiotoxicity
•Analyse performance of different in vitro models to detect human hepatotoxic drugs
•Human stem cell derived cardiomyocytes
•Regulatory DDI Guidance(s) for drug transporters - an overview review of current FDA, EMA and JMHLW (Japan) guidance for industry
•Mitigating errors in early human dose predictions and setting the criteria for ADME end points

In addition, don’t miss the post-conference workshop taking place on the 1st July:
• ADME(T) Strategies for Pharmacological Space Beyond Ro5 and Eukaryotic Enzyme Inhibitors
Workshop Leader: Constance Höfer, Chief Development Officer, Priaxon AG

HOW TO REGISTER
Register online at http://www.smi-online.co.uk/goto/2015admet1.asp
Contact Magdalena Georgieva on +44 (0)20 7827 6148 or email mgeorgieva@smi-online.co.uk



Exhibitors

Araz Raoof, Head Scientific Affairs & Analysis, Janssen Pharmaceutical, Professor Ian D. Wilson, Professor of Drug Metabolism, Imperial College London, Laurent Salphati, Senior Scientist, Genentech, Thierry Lave, Global Head DMPK & Tox Project Leaders and Modelling & Simulation, F. Hoffmann-La Roche, Peter Clements, Director of Pathology, GSK, Stephen Fowler, Group Leader, In Vitro ADME, F. Hoffmann-La Roche, •Franck Atienzar, Associate Director In Silico In Vitro Toxicology, UCB BioPharma SPRL, Peter Hoffmann, Executive Director, Pre-Clinical Safety, Novartis Institutes for BioMedical Research, Mario Monshouwer, Senior Director Drug Metabolism Pharmacokinetics & Bioanalysis, Johnson & Johnson

Go to event website